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Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial.

Antcliffe, DB; Burnham, KL; Al-Beidh, F; Santhakumaran, S; Brett, SJ; Hinds, CJ; Ashby, D; Knight, JC; Gordon, AC (2019-04-15)

RATIONALE: There remains uncertainty about the role of corticosteroids in sepsis with clear beneficial effects on shock duration, but conflicting survival effects. Two transcriptomic sepsis response signatures (SRSs) have ...