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Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol.

Playford, RJ; Batten, JJ; Freeman, TC; Beardshall, K; Vesey, DA; Fenn, GC; Baron, JH; Calam, J (1991-11)

Pancreatic secretory trypsin inhibitor (PSTI) is a potent protease inhibitor that also has growth promoting activity. It has recently been identified in the foveolar cells of the stomach, which secrete mucus. We examined ...

Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice.

Freeman, TC; Playford, RJ; Quinn, C; Beardshall, K; Poulter, L; Young, J; Calam, J (1990-11)

We studied the distribution of pancreatic secretory trypsin inhibitor (PSTI) in the epithelia of the gastrointestinal tract and determined whether PSTI is secreted into gastric juice. PSTI was measured by a specific ...