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Meta-DiSc: a software for meta-analysis of test accuracy data.
(2006-07-12)
BACKGROUND: Systematic reviews and meta-analyses of test accuracy studies are increasingly being recognised as central in guiding clinical practice. However, there is currently no dedicated and comprehensive software for ...
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
(2019-07-30)
BACKGROUND: Acute gastrointestinal (GI) bleeding is an important cause of mortality worldwide. Bleeding can occur from the upper or lower GI tract, with upper GI bleeding accounting for most cases. The main causes include ...
Clinical trial designs for testing of products for dentine hypersensitivity--a review.
(1997)
Dentine hypersensitivity (DH) is a perplexing clinical entity. There is no doubt that patients self-report discomfort arising from various stimuli, but the highly subjective nature of the condition makes it extremely ...
Using systematic data categorisation to quantify the types of data collected in clinical trials: the DataCat project.
(2020-06-16)
BACKGROUND: Data collection consumes a large proportion of clinical trial resources. Each data item requires time and effort for collection, processing and quality control procedures. In general, more data equals a heavier ...
A flexible model for multivariate interval-censored survival times with complex correlation structure.
(2007-02-10)
We focus on the analysis of multivariate survival times with highly structured interdependency and subject to interval censoring. Such data are common in developmental genetics and genetic epidemiology. We propose a flexible ...
Global, regional, and national burden of suicide mortality 1990 to 2016: systematic analysis for the Global Burden of Disease Study 2016
(BMJ Publishing Group, 2019-02-06)
OBJECTIVES: To use the estimates from the Global Burden of Disease Study 2016 to describe patterns of suicide mortality globally, regionally, and for 195 countries and territories by age, sex, and Socio-demographic index, ...