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Genome-wide association study of suicidal behaviour severity in mood disorders.
(2021-03-30)
OBJECTIVE: Suicide is a major public health problem and it has a prominent genetic component. We performed a genome-wide association study (GWAS) of suicidal behaviour severity. METHODS: Suicide behaviour severity was ...
Pharmacogenetics of antidepressant response: A polygenic approach.
(2017-04-03)
BACKGROUND: Major depressive disorder (MDD) has a high personal and socio-economic burden and >60% of patients fail to achieve remission with the first antidepressant. The biological mechanisms behind antidepressant response ...