Browsing by Author "Bulmer, DC"
Now showing items 1-11 of 11
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Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.
Balemans, D; Mondelaers, SU; Cibert-Goton, V; Stakenborg, N; Aguilera-Lizarraga, J; Dooley, J; Liston, A; Bulmer, DC; Vanden Berghe, P; Boeckxstaens, GE (2017-10-19)Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis. The underlying mechanisms are unclear, although ... -
Ex vivo study of human visceral nociceptors
McGuire, C; Boundouki, G; Hockley, JRF; Reed, D; Cibert-Goton, V; Peiris, M; Kung, V; Broad, J; Aziz, Q; Chan, C (2018-01) -
The extracellular matrix glycoprotein tenascin-X regulates peripheral sensory and motor neurones.
Aktar, R; Peiris, M; Fikree, A; Cibert-Goton, V; Walmsley, M; Tough, IR; Watanabe, P; Araujo, EJA; Mohammed, SD; Delalande, J-M (2018-09)KEY POINTS: Tenascin-X (TNX) is an extracellular matrix glycoprotein with anti-adhesive properties in skin and joints. Here we report the novel finding that TNX is expressed in human and mouse gut tissue where it is exclusive ... -
Functional and anatomical deficits in visceral nociception with age: a mechanism of silent appendicitis in the elderly?
Cibert-Goton, V; Kung, VWS; McGuire, C; Hockley, JRF; Tranter, MM; Dogra, H; Belai, A; Blackshaw, LA; Sanger, GJ; Knowles, CH (2020-04) -
Histamine Receptor H1-Mediated Sensitization of TRPV1 Mediates Visceral Hypersensitivity and Symptoms in Patients With Irritable Bowel Syndrome
Wouters, MM; Balemans, D; Van Wanrooy, S; Dooley, J; Cibert-Goton, V; Alpizar, YA; Valdez-Morales, EE; Nasser, Y; Van Veldhoven, PP; Vanbrabant, W (2016-04) -
Multiple roles for Na(V)1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease-derived stimuli
Hockley, JRF; Boundouki, G; Cibert-Goton, V; McGuire, C; Yip, PK; Chan, C; Tranter, M; Wood, JN; Nassar, MA; Blackshaw, LA (2014-10) -
P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors
Hockley, JRF; Tranter, MM; McGuire, C; Boundouki, G; Cibert-Goton, V; Thaha, MA; Blackshaw, LA; Michael, GJ; Baker, MD; Knowles, CH (2016-02-24) -
Peripheral K<sub>V</sub>7 channels regulate visceral sensory function in mouse and human colon
Peiris, M; Hockley, JRF; Reed, DE; Smith, ESJ; Bulmer, DC; Blackshaw, LA (2017) -
Transcriptomic profiling reveals a pro-nociceptive role for Angiotensin II in inflammatory bowel disease
Higham, JP; Bhebhe, CN; Gupta, RA; Tranter, M; Barakat, FM; Dogra, H; Bab, N; Wozniak, E; Barker, KH; Wilson, CH -
Visceral and somatic pain modalities reveal Na(V)1.7-independent visceral nociceptive pathways
Hockley, JRF; Gonzalez-Cano, R; McMurray, S; Tejada-Giraldez, MA; McGuire, C; Torres, A; Wilbrey, AL; Cibert-Goton, V; Nieto, FR; Pitcher, T (2017-04-15) -
The voltage-gated sodium channel Na(V)1.9 in visceral pain
Hockley, JRF; Winchester, WJ; Bulmer, DC (2016-03)