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Now showing items 9549-9568 of 40509
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DNA Origami Nanoarrays for Multivalent Investigations of Cancer Cell Spreading with Nanoscale Spatial Resolution and Single- Molecule Control
(American Chemical Society, 2018-12)We present a strategy for the fabrication of biomimetic nanoarrays, based on the use of DNA origami, that permits the multivalent investigation of ligand–receptor molecule interactions in cancer cell spreading, with nanoscale ... -
The DNA replication initiation protein DnaD recognises a specific strand of the Bacillus subtilis chromosome origin
(Oxford University Press, 2023)Genome replication is a fundamental biological activity shared by all organisms. Chromosomal replication proceeds bidirectionally from origins, requiring the loading of two helicases, one for each replisome. However, the ... -
DNA typing of the human small intestinal protozoan parasite Giardia lamblia
(Queen Mary University of London, 1995)At present there is no satisfactory means of typing strains of Giardia lamblia which can explain the broad range of clinical symptoms seen in giardiasis or which can identify genotypes in epidemiological studies. This ... -
DNA-Directed Assembly of Carbon Nanotube-Protein Hybrids.
(MDPI, 2021-06-29)Here, we report the controlled assembly of SWCNT-GFP hybrids employing DNA as a linker. Two distinct, enriched SWCNTs chiralities, (6,5), (7,6), and an unsorted SWCNT solution, were selectively functionalized with DNA and ... -
DNA-Driven Dynamic Assembly of MoS2 Nanosheets
(Royal Society of Chemistry, 2020-03-27) -
DNA-Wrapped Single-Walled Carbon Nanotube Assemblies
(2017-05-10) -
DNA‐Templated [2 2] Photocycloaddition: A Straightforward Entry into the Aplysinopsin Family of Natural Products
(Wiley, 2018-07-10)Biosynthetic considerations inspired us to harness the template properties offered by DNA to promote a [2+2] photo‐induced cycloaddition. The method was developed based on the dimerization of (E)‐aplysinopsin, which was ... -
DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster.
(2016-08-01)Pancreatic ductal adenocarcinoma (PDAC) and other carcinomas are hierarchically organized, with cancer stem cells (CSC) residing at the top of the hierarchy, where they drive tumor progression, metastasis, and chemoresistance. ...