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Now showing items 30997-31016 of 40424
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Regulation of breast tumour cell survival by AP-2 transcription factors
(Queen Mary University of London, 2010)AP-2 transcription factors are crucial regulators of embryonic development and also play important roles in human neoplasia. Over-expression of AP-2α and AP-2γ in primary breast cancer (BC) correlates with expression of ... -
Regulation of cardiomyocyte adhesion and mechanosignalling through distinct nanoscale behaviour of integrin ligands mimicking healthy or fibrotic extracellular matrix.
(2022-11-21)The stiffness of the cardiovascular environment changes during ageing and in disease and contributes to disease incidence and progression. Changing collagen expression and cross-linking regulate the rigidity of the cardiac ... -
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia.
(2014)The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. ... -
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia.
(2014-12-11)The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. ... -
Regulation of Cross-Border Law Enforcement: ‘Locks’ and ‘Dams’ to Regional and International Flows of Policing
(Taylor & Francis (Routledge), 2017-06-28)Trans-jurisdictional policing can eventuate within a number of different environments: in federal states comprising different jurisdictions, in bilateral and multilateral settings and in regional contexts, for example, in ... -
Regulation of cyclic electron flow through ferredoxin redox partners
(2023)Photosynthetic organisms must balance their electron transport between linear and cyclic electron flow. Linear electron flow (LEF) is required for carbon fixation whereas cyclic electron flow (CEF) must be upregulated under ... -
The regulation of external audit in the UK and US and a proposal for a new audit model
(Queen Mary University of London, 2018-06-14)This thesis is the study of the role and regulation of the external audit in the UK and US. It argues that the current audit model is fundamentally flawed, which has a negative impact on the quality of financial audits. ... -
The regulation of franchising in the European Union
(2011)Business format franchising is a specific, distinct and uniform type of commercial activity with significant economic impact in the European Union. It stimulates economic activity by offering significant advantages to ... -
Regulation of gluconeogenesis in type 2 diabetes mellitus: An investigation of the role of corticosteroids?
(Queen Mary University of London, 2012)Type 2 diabetes mellitus (T2DM) is a complex disease involving various physiological factors, hormones and metabolites. Over expression of key gluconeogenic enzymes, such as PEPCK, cause features of T2DM including obesity ... -
Regulation of hedge funds in the US, the UK and the EU.
(Queen Mary University of London, 2013)Two major trends have emerged in the hedge fund industry over the last ten years. On the one hand, this industry became one of the most creative and innovative fields in international finance. Due to its fast growth and ... -
Regulation of human fibroblast insulin-like growth factor (IGF)-binding proteins by IGF-1 and cytokines, mechanisms of action and effects upon IGF bioactivity
(Queen Mary University of London, 1995)The insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth ... -
The regulation of insider trading in corporate securities
(1977)Firstly it is necessary to examine insider trading in corporate securities in it's social and economic context. Before any discussion of substantive regulation can meaningfully take place it 1s necessary to consider ... -
The Regulation of New Electronic Payment Services in China
(Queen Mary University of London, 2014-07-08)Due to the lack of efficient offline payment services for small value payment, and along with the booming of the Internet and telecommunications technologies, new electronic payment services and instruments are becoming ... -
Regulation of oligopolies in the EU electronic communications markets: the current framework does not adequately address the oligopoly problem.
(Queen Mary University of London, 2014-12)The present work has examined the thesis that the current framework for the regulation of SMP under EU law on electronic communications does not address the oligopoly problem in full. Under the SMP framework for electronic ...
