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Now showing items 1347-1366 of 40240
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Analysis of circulating protein aggregates as a route of investigation into neurodegenerative disorders.
(Oxford University Press, 2021-07-09)Plasma proteome composition reflects the inflammatory and metabolic state of the organism and can be predictive of system-level and organ-specific pathologies. Circulating protein aggregates are enriched with neurofilament ... -
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
(2013)Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features. -
Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry.
(2023-08-26)BACKGROUND: Investigation for the presence of asthma comorbidities is recommended by GINA as their presence can complicate asthma management. OBJECTIVE: To understand the prevalence and pattern of comorbidities and ... -
Analysis of Computer Experiments with Smooth Emulators
(2022)This thesis is concerned with the methodology of smooth emulators for computer experiments. The work in this thesis is categorized into two parts. The first and the main part comprises methods with smooth emulators for the ... -
Analysis of exome-sequenced UK Biobank subjects implicates genes affecting risk of hyperlipidaemia.
(2020-07-29)Rare genetic variants in LDLR, APOB and PCSK9 are known causes of familial hypercholesterolaemia and it is expected that rare variants in other genes will also have effects on hyperlipidaemia risk although such genes remain ... -
Analysis of Exosomes and molecular biomarkers in saliva and the gingival crevicular fluid in patients with periodontal disease.
Abstract Aim: The aim of this pilot study is to evaluate if biomarker signature(s) of exosomal miRNAs, IL-1β and IL-6 isolated from GCF and saliva exist and can be used as feasible biomarkers of periodontal treatment. ...