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Now showing items 11721-11740 of 40240
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Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer.
(2017-10-17)Colorectal cancer (CRC) is a biologically and clinically heterogeneous disease. Even though many recurrent genomic alterations have been identified that may characterize distinct subgroups, their biological impact and ... -
Epigenetic variation associated with genetic and environmental factors in the aetiology of Type 2 diabetes.
(Queen Mary University of London, 2013-02)Type 2 diabetes, as a complex disease, has a range of genetic and environmental factors that underpin its aetiology. It is hoped that the emerging study of epigenetic processes will provide the necessary mechanistic insight ... -
Epigenetics of Royalty
(2010-11) -
Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study.
(2019-12)Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, ... -
Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States.
(2023-11-06)BACKGROUND: Methylation levels may be associated with and serve as markers to predict risk of progression of precancerous cervical lesions. We conducted an epigenome-wide association study (EWAS) of CpG methylation and ... -
The Epigenomic Analysis of Human Obesity
(2017-09) -
Episiotomy practices in France: epidemiology and risk factors in non-operative vaginal deliveries
(Springer Nature, 2020-11-19)Episiotomy use has decreased due to the lack of evidence on its protective effects from maternal obstetric anal sphincter injuries. Indications for episiotomy vary considerably and there are a great variety of factors ... -
Epitaxial Templating of C-60 with a Molecular Monolayer
(2016-09-01) -
Epithelial cell adaptation to supernumerary centrosomes
(Queen Mary University of London, 2017-10-26)The centrosome is the main microtubule-organising centre in animal cells; important to assemble a bipolar mitotic spindle ensuring proper chromosome segregation and genomic stability. Whereas correct centrosome number ... -
Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines.
(2003-10-02)While alpha- and beta-synuclein largely overlap in their expression in the vertebrate brain, only alpha-synuclein accumulates in the fibrillar aggregates typical of Parkinson's disease. It is thus critical to have immunological ... -
Epochal Aesthetics: Affectual Infrastructures of the Anthropocene
(e-flux, 2017-03-29)The Anthropocene renders visible new architectures of time and matter, both sedimenting existing genealogies of global-world-space and radically reorganizing an imagination of the scope and material duration of what the ...