• RNA sequencing and lipidomics uncovers novel pathomechanisms in recessive X-linked ichthyosis 

  McGeoghan, F; Camera, E; Maiellaro, M; Menon, M; Huang, M; Dewan, P; Ziaj, S; Caley, MP; Donaldson, M; Enright, AJ (Frontiers Media, 2023-06-07)

  Recessive X-linked ichthyosis (RXLI), a genetic disorder caused by deletion or point mutations of the steroid sulfatase (STS) gene, is the second most common form of ichthyosis. It is a disorder of keratinocyte cholesterol ...

• Molecular Modeling Studies to Probe the Binding Hypothesis of Novel Lead Compounds against Multidrug Resistance Protein ABCB1. 

  Cheema, Y; Linton, KJ; Jabeen, I (2024-01-16)

  The expression of drug efflux pump ABCB1/P-glycoprotein (P-gp), a transmembrane protein belonging to the ATP-binding cassette superfamily, is a leading cause of multidrug resistance (MDR). We previously curated a dataset ...

• Structural basis for the modulation of MRP2 activity by phosphorylation and drugs. 

  Mazza, T; Roumeliotis, TI; Garitta, E; Drew, D; Rashid, ST; Indiveri, C; Choudhary, JS; Linton, KJ; Beis, K (2024-03-04)

  Multidrug resistance-associated protein 2 (MRP2/ABCC2) is a polyspecific efflux transporter of organic anions expressed in hepatocyte canalicular membranes. MRP2 dysfunction, in Dubin-Johnson syndrome or by off-target ...

• Patient-Specific Non-Invasive Estimation of the Aortic Blood Pressure Waveform by Ultrasound and Tonometry 

  Zhou, S; Xu, K; Fang, Y; Alastruey, J; Vennin, S; Yang, J; Wang, J; Xu, L; Wang, X; Greenwald, SE (2024-02-01)

• Why are squamous cancers so aggressive in recessive dystrophic epidermolysis bullosa? Can we find new therapeutic approaches? 

  O'Shaughnessy, RFL (Oxford University Press, 2023-10-13)

• Decosus: An R Framework for Universal Integration of Cell Proportion Estimation Methods 

  Anene, CA; Taggart, E; Harwood, CA; Pennington, DJ; Wang, J (2022)

• Pachyonychia Congenita: A Research Agenda Leading to New Therapeutic Approaches. 

  O'Toole, EA; Kelsell, DP; Caterina, MJ; de Brito, M; Hansen, D; Hickerson, RP; Hovnanian, A; Kaspar, R; Lane, EB; Paller, AS (2023-12-14)

  Pachyonychia congenita (PC) is a dominantly inherited genetic disorder of cornification. PC stands out among other genodermatoses because despite its rarity, it has been the focus of a very large number of pioneering ...

• Skin fibroblast functional heterogeneity in health and disease 

  Bensa, T; Tekkela, S; Rognoni, E (2023)

• COACT: Coronary artery centerline tracker. 

  Li, X; Ji, L; Zhang, R; You, H; Xu, L; Greenwald, SE; Sun, Y; Zhang, L; Yang, B (Wiley, 2023-12-07)

  BACKGROUND: The curved planar reformation (CPR) technique is one of the most commonly used methods in clinical practice to locate coronary arteries in medical images. PURPOSE: The artery centerline is the cornerstone for ...

• Editorial: Novel aspects of the immunological and structural barrier of the epidermis. 

  O'Shaughnessy, R; Common, J; Gutowska-Owsiak, D (2023)

• TSP-UDANet: two-stage progressive unsupervised domain adaptation network for automated cross-modality cardiac segmentation 

  Wang, Y; Zhang, Y; Xu, L; Qi, S; Yao, Y; Qian, W; Greenwald, SE; Qi, L (2023)

• IL-4 stimulates IL-1R2 upregulation in atopic dermatitis keratinocytes 

  Baruah, K; Koh, L; Tham, K; O'Shaughnessy, R; O'Toole, E; Common, JE (2023)

• AKT1-dependent protease control of skin barrier function and inflammation in atopic dermatitis 

  Tachie-Menson, T; Azizah, A; Hughes, A; O'Shaughnessy, R (2023)

• Automatic coronary artery segmentation of CCTA images using UNet with a local contextual transformer 

  Wang, Q; Xu, L; Wang, L; Yang, X; Sun, Y; Yang, B; Greenwald, SE

• Dynamic impact of chronic inflammation on epidermal autophagy pathway 

  Uddin, N; Ostano, P; Chiorino, G; di Domizio, J; Gilliet, M; Philpott, M; Hannen, R; Bergamaschi, D (2023)

• O13 JAK inhibitors to restore skin barrier function in ARCI 

  Giusto, E; Enjalbert, F; Rognoni, E; Caley, M; O’Toole, E (Oxford University Press (OUP), 2023-07-07)

• Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism. 

  Sipilä, K; Rognoni, E; Jokinen, J; Tewary, M; Vietri Rudan, M; Talvi, S; Jokinen, V; Dahlström, KM; Liakath-Ali, K; Mobasseri, A (2022-06-20)

  Stem cell renewal and differentiation are regulated by interactions with the niche. Although multiple cell populations have been identified in distinct anatomical compartments, little is known about niche-specific molecular ...

• 297 Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage 

  Rognoni, E; Goss, G; Hiratsuka, T; Lui, P; Hawkshaw, N; Pilkington, S; Ali, N; Rhodes, L; Watt, F (Elsevier, 2021-10)

• 591 Exploring the molecular basis for the dermal fibroblast state switch 

  Kirk, T; Ahmed, A; Connelly, J; Rognoni, E (Elsevier, 2022-12)

• 1458 Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis 

  Ahmed, A; Kirk, T; Forster, L; O'Toole, E; Gupta, H; Rognoni, E (Elsevier, 2023-05)

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