Browsing Centre for Biochemical Pharmacology by Subject "Heart failure"
Now showing items 1-3 of 3
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Nox2-deficient Tregs improve heart transplant outcomes via their increased graft recruitment and enhanced potency.
(2021-08-10)Nox2 is a ROS-generating enzyme, deficiency of which increases suppression by Tregs in vitro and in an in vivo model of cardiac remodelling. Since Tregs have emerged as a candidate therapy in autoimmunity and transplantation, ... -
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure.
(2021-08-06)Elevated intracellular Na (Nai) and metabolic impairment are interrelated pathophysiological features of the failing heart (HF). There have been a number of studies showing that myocardial sodium elevation subtly affects ...