Browsing Centre for Biochemical Pharmacology by Subject "Dendritic Cells"

Now showing items 1-4 of 4

    • An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. 

      Subramanian, M; Hayes, CD; Thome, JJ; Thorp, E; Matsushima, GK; Herz, J; Farber, DL; Liu, K; Lakshmana, M; Tabas, I (2014-03)
      The phagocytosis of apoptotic cells (ACs), or efferocytosis, by DCs is critical for self-tolerance and host defense. Although many efferocytosis-associated receptors have been described in vitro, the functionality of these ...

    • Dendritic cells and adipose tissue. 

      Sundara Rajan, S; Longhi, MP (2016-12)
      Visceral adipose tissue inflammation in obesity is an established risk factor for metabolic syndrome, which can include insulin resistance, type 2 diabetes, hypertension and cardiovascular diseases. With obesity and related ...

    • The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and Function. 

      Aksoy, E; Saveanu, L; Manoury, B (2018)
      Phosphoinositide-3 kinases (PI3Ks) generate 3-phosphorylated phosphoinositide lipids that are implicated in many biological processes in homeostatic states and pathologies such as cancer, inflammation and autoimmunity. ...

    • Vitamin D Counteracts an IL-23-Dependent IL-17A+IFN-γ+ Response Driven by Urban Particulate Matter. 

      Mann, EH; Ho, T-R; Pfeffer, PE; Matthews, NC; Chevretton, E; Mudway, I; Kelly, FJ; Hawrylowicz, CM (American Thoracic Society, 2017-09-01)
      Urban particulate matter (UPM) air pollution and vitamin D deficiency are detrimentally associated with respiratory health. This is hypothesized to be due in part to regulation of IL-17A, which UPM is reported to promote. ...